A virus or more in (nearly) every cell: ubiquitous networks of virus-host interactions in extreme environments.

ABSTRACT: The application of viral and cellular metagenomics to natural environments has expanded our understanding of the structure, functioning, and diversity of microbial and viral communities. The high diversity of many communities, e.g., soils, surface ocean waters, and animal-associated microbiomes, make it difficult to establish virus-host associations at the single cell (rather than population) level, assign cellular hosts, or determine the extent of viral host range from metagenomics studies alone. Here, we combine single-cell sequencing with environmental metagenomics to characterize the structure of virus-host associations in a Yellowstone National Park (YNP) hot spring microbial community. Leveraging the relatively low diversity of the YNP environment, we are able to overlay evidence at

SUBMITTER: Munson-McGee JH 

PROVIDER: S-EPMC6018696 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature