Specialized plant biochemistry drives gene clustering in fungi.

ABSTRACT: The fitness and evolution of prokaryotes and eukaryotes are affected by the organization of their genomes. In particular, the physical clustering of genes can coordinate gene expression and can prevent the breakup of co-adapted alleles. Although clustering may thus result from selection for phenotype optimization and persistence, the impact of environmental selection pressures on eukaryotic genome organization has rarely been systematically explored. Here, we investigated the organization of fungal genes involved in the degradation of phenylpropanoids, a class of plant-produced secondary metabolites that mediate many ecological interactions between plants and fungi. Using a novel gene cluster detection method, we identified 1110 gene clusters and many conserved combinations of clusters in

SUBMITTER: Gluck-Thaler E 

PROVIDER: S-EPMC6018750 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature