Genome, transcriptome and proteome: the rise of omics data and their integration in biomedical sciences.

ABSTRACT: Advances in the technologies and informatics used to generate and process large biological data sets (omics data) are promoting a critical shift in the study of biomedical sciences. While genomics, transcriptomics and proteinomics, coupled with bioinformatics and biostatistics, are gaining momentum, they are still, for the most part, assessed individually with distinct approaches generating monothematic rather than integrated knowledge. As other areas of biomedical sciences, including metabolomics, epigenomics and pharmacogenomics, are moving towards the omics scale, we are witnessing the rise of inter-disciplinary data integration strategies to support a better understanding of biological systems and eventually the development of successful precision medicine. This review cuts across the

SUBMITTER: Manzoni C 

PROVIDER: S-EPMC6018996 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature