Low Serum Calcium and Magnesium Levels and Rupture of Intracranial Aneurysms.

ABSTRACT:

Background and purpose

Both low serum calcium and magnesium levels have been associated with the extent of bleeding in patients with intracerebral hemorrhage, suggesting hypocalcemia- and hypomagnesemia-induced coagulopathy as a possible underlying mechanism. We hypothesized that serum albumin-corrected total calcium and magnesium levels are associated with ruptured intracranial aneurysms.

Methods

The medical records of 4701 patients, including 1201 prospective patients, diagnosed at the Brigham and Women's Hospital and Massachusetts General Hospital between 1990 and 2016 were reviewed and analyzed. One thousand two hundred seventy-five patients had available serum calcium, magnesium, and albumin values within 1 day of diagnosis. Individuals were divided into cases with rupt

SUBMITTER: Can A 

PROVIDER: S-EPMC6019530 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature