Evidence of transcranial direct current stimulation-generated electric fields at subthalamic level in human brain in vivo.

ABSTRACT:

Background

Transcranial direct current stimulation (tDCS) is a promising brain modulation technique for several disease conditions. With this technique, some portion of the current penetrates through the scalp to the cortex and modulates cortical excitability, but a recent human cadaver study questions the amount. This insufficient intracerebral penetration of currents may partially explain the inconsistent and mixed results in tDCS studies to date. Experimental validation of a transcranial alternating current stimulation-generated electric field (EF) in vivo has been performed on the cortical (using electrocorticography, ECoG, electrodes), subcortical (using stereo electroencephalography, SEEG, electrodes) and deeper thalamic/subthalamic levels (using DBS electrodes). However, tDC

SUBMITTER: Chhatbar PY 

PROVIDER: S-EPMC6019625 | biostudies-literature | 2018 Jul - Aug

REPOSITORIES: biostudies-literature