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The Alga Ochromonas danica Produces Bromosulfolipids.


ABSTRACT: Many halogenases interchangeably incorporate chlorine and bromine into organic molecules. On the basis of an unsubstantiated report that the alga Ochromonas danica, a prodigious producer of chlorosulfolipids, was able to produce bromosulfolipids, we have investigated the promiscuity of its halogenases toward bromine incorporation. We have found that bromosulfolipids are produced with the exact positional and stereochemical selectivity as in the chlorosulfolipid danicalipin A when this alga is grown under modified conditions containing excess bromide ion.

SUBMITTER: White AR 

PROVIDER: S-EPMC6020021 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature

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The Alga Ochromonas danica Produces Bromosulfolipids.

White Alexander R AR   Duggan Brendan M BM   Tsai Shiou-Chuan SC   Vanderwal Christopher D CD  

Organic letters 20160218 5


Many halogenases interchangeably incorporate chlorine and bromine into organic molecules. On the basis of an unsubstantiated report that the alga Ochromonas danica, a prodigious producer of chlorosulfolipids, was able to produce bromosulfolipids, we have investigated the promiscuity of its halogenases toward bromine incorporation. We have found that bromosulfolipids are produced with the exact positional and stereochemical selectivity as in the chlorosulfolipid danicalipin A when this alga is gr  ...[more]

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