PanACEA: a bioinformatics tool for the exploration and visualization of bacterial pan-chromosomes.

ABSTRACT:

Background

Bacterial pan-genomes, comprised of conserved and variable genes across multiple sequenced bacterial genomes, allow for identification of genomic regions that are phylogenetically discriminating or functionally important. Pan-genomes consist of large amounts of data, which can restrict researchers ability to locate and analyze these regions. Multiple software packages are available to visualize pan-genomes, but currently their ability to address these concerns are limited by using only pre-computed data sets, prioritizing core over variable gene clusters, or by not accounting for pan-chromosome positioning in the viewer.

Results

We introduce PanACEA (Pan-genome Atlas with Chromosome Explorer and Analyzer), which utilizes locally-computed interactive web-pages to v

SUBMITTER: Clarke TH 

PROVIDER: S-EPMC6020400 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature