Characterization of Wild and Captive Baboon Gut Microbiota and Their Antibiotic Resistomes.

ABSTRACT: Environmental microbes have harbored the capacity for antibiotic production for millions of years, spanning the evolution of humans and other vertebrates. However, the industrial-scale use of antibiotics in clinical and agricultural practice over the past century has led to a substantial increase in exposure of these agents to human and environmental microbiota. This perturbation is predicted to alter the ecology of microbial communities and to promote the evolution and transfer of antibiotic resistance (AR) genes. We studied wild and captive baboon populations to understand the effects of exposure to humans and human activities (e.g., antibiotic therapy) on the composition of the primate fecal microbiota and the antibiotic-resistant genes that it collectively harbors (the "resistome"). Us

SUBMITTER: Tsukayama P 

PROVIDER: S-EPMC6020475 | biostudies-literature | 2018 May-Jun

REPOSITORIES: biostudies-literature