Tellurium notebooks-An environment for reproducible dynamical modeling in systems biology.

ABSTRACT: The considerable difficulty encountered in reproducing the results of published dynamical models limits validation, exploration and reuse of this increasingly large biomedical research resource. To address this problem, we have developed Tellurium Notebook, a software system for model authoring, simulation, and teaching that facilitates building reproducible dynamical models and reusing models by 1) providing a notebook environment which allows models, Python code, and narrative to be intermixed, 2) supporting the COMBINE archive format during model development for capturing model information in an exchangeable format and 3) enabling users to easily simulate and edit public COMBINE-compliant models from public repositories to facilitate studying model dynamics, variants and test cases. Tel

SUBMITTER: Medley JK 

PROVIDER: S-EPMC6021116 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature