Innovation in neglected tropical disease drug discovery and development.

ABSTRACT:

Background

Neglected tropical diseases (NTDs) are closely related to poverty and affect over a billion people in developing countries. The unmet treatment needs cause high mortality and disability thereby imposing a huge burden with severe social and economic consequences. Although coordinated by the World Health Organization, various philanthropic organizations, national governments and the pharmaceutical industry have been making efforts in improving the situation, the control of NTDs is still inadequate and extremely difficult today. The lack of safe, effective and affordable medicines is a key contributing factor. This paper reviews the recent advances and some of the challenges that we are facing in the fight against NTDs.

Main body

In recent years, a number of innovati

SUBMITTER: Weng HB 

PROVIDER: S-EPMC6022351 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature