Management of financial conflicts of interests in clinical practice guidelines in Germany: results from the public database GuidelineWatch.

ABSTRACT:

Background

The reliability of clinical practice guidelines has been disputed because guideline panel members are often burdened with financial conflicts of interest (COI). Current recommendations for COI regulation advise not only detailed declaration but also active management of conflicts. To continuously assess COI declaration and management in German guidelines we established the public database LeitlinienWatch (GuidelineWatch).

Methods

We analyzed all German guidelines at the highest methodological level (S3) that included recommendations for pharmacological therapy (n = 67) according to five criteria: declaration and assessment of COI, composition of the guideline development group, independence of the coordinators and lead authors, imposed abstentions because of COI a

SUBMITTER: Napierala H 

PROVIDER: S-EPMC6022410 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature