An In Vitro Model for Candida albicans⁻Streptococcus gordonii Biofilms on Titanium Surfaces.

ABSTRACT: The oral cavity serves as a nutrient-rich haven for over 600 species of microorganisms. Although many are essential to maintaining the oral microbiota, some can cause oral infections such as caries, periodontitis, mucositis, and endodontic infections, and this is further exacerbated with dental implants. Most of these infections are mixed species in nature and associated with a biofilm mode of growth. Here, after optimization of different parameters including cell density, growth media, and incubation conditions, we have developed an in vitro model of C. albicans⁻S. gordonii mixed-species biofilms on titanium discs that is relevant to infections of peri-implant diseases. Our results indicate a synergistic effect for the development of biofilms when both microorganisms were seeded together,

SUBMITTER: Montelongo-Jauregui D 

PROVIDER: S-EPMC6023327 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature