Comment on 'YcgC represents a new protein deacetylase family in prokaryotes'.

ABSTRACT: Lysine acetylation is a post-translational modification that is conserved from bacteria to humans. It is catalysed by the activities of lysine acetyltransferases, which use acetyl-CoA as the acetyl-donor molecule, and lysine deacetylases, which remove the acetyl moiety. Recently, it was reported that YcgC represents a new prokaryotic deacetylase family with no apparent homologies to existing deacetylases (Tu et al., 2015). Here we report the results of experiments which demonstrate that YcgC is not a deacetylase.

SUBMITTER: Kremer M 

PROVIDER: S-EPMC6023612 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature