Serological, genetic and clinical associations with increased health-care resource utilization in inflammatory bowel disease.

ABSTRACT:

Objective

Inflammatory bowel diseases (IBD) are associated with significant morbidity and economic burden. The variable course of IBD creates a need for predictors of clinical outcomes and health resource utilization (HRU) to guide treatment decisions. We aimed to identify clinical, serological or genetic markers associated with inpatient resource utilization in patients with ulcerative colitis (UC) and Crohn's disease (CD).

Methods

Patients with IBD with available genetic and serological data who had at least one emergency department visit or hospitalization in a 3-year period were included. The primary outcome measure was HRU, as measured by the All Patient Refined Diagnosis Related Group classification system. Univariate and multivariate linear and logistic regression mod

SUBMITTER: Gu P 

PROVIDER: S-EPMC6023617 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature