Noninvasive Electric Current Induction for Low-Frequency Tissue Conductivity Reconstruction: Is It Feasible With a TMS-MRI Setup?

ABSTRACT: Noninvasive quantification of subject-specific low-frequency brain tissue conductivity ( σLF ) will be valuable in different fields, for example, neuroscience. Magnetic resonance (MR)-electrical impedance tomography allows measurements of σLF . However, the required high level of direct current injection leads to an undesirable pain sensation. Following the same principles, but avoiding pain sensation, we evaluate the feasibility of inductively inducing currents using a transcranial magnetic stimulation (TMS) device and recording the magnetic field variations arising from the induced tissue eddy currents using a standard 3 T MR scanner. Using simulations, we characterize the strength of the incident TMS magnetic field arising from the current running in the TMS coil, the strength of the in

SUBMITTER: Mandija S 

PROVIDER: S-EPMC6024402 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature