Effects of fermented ginseng root and ginseng berry on obesity and lipid metabolism in mice fed a high-fat diet.

ABSTRACT:

Background

Previous studies have shown that both ginseng root and ginseng berry exhibit antiobesity and antidiabetic effects. However, a direct comparison of the efficacy and mechanisms between the root and the berry after oral administration remains to be illuminated.

Methods

In this study, we observed the effects of fermented ginseng root (FGR) and fermented ginseng berry (FGB) on obesity and lipid metabolism in high-fat diet induced obese mice.

Results

FGR and FGB significantly inhibited the activity of pancreatic lipase in vitro. Both FGR and FGB significantly suppressed weight gain and excess food intake and improved hypercholesterolemia and fatty liver, while only FGR significantly attenuated hyperglycemia and insulin resistance. Both FGR and FGB signific

SUBMITTER: Li Z 

PROVIDER: S-EPMC6026359 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature