Tuning the Bandgap of Photo-Sensitive Polydopamine/Ag₃PO₄/Graphene Oxide Coating for Rapid, Noninvasive Disinfection of Implants.

ABSTRACT: Bacterial infection and associated complications are threats to human health especially when biofilms form on biomedical devices and artificial implants. Herein, a hybrid polydopamine (PDA)/Ag₃PO₄/graphene oxide (GO) coating is designed and constructed to achieve rapid bacteria killing and eliminate biofilms in situ. By varying the amount of GO in the hybrid coating, the bandgap can be tuned from 2.52 to 2.0 eV so that irradiation with 660 nm visible light produces bacteria-killing effects synergistically in concert with reactive oxygen species (ROS). GO regulates the release rate of Ag⁺ to minimize the cytotoxicity while maintaining high antimicrobial activity, and a smaller particle size enhances the yield of ROS. After irradiation with 660 nm visible lig

SUBMITTER: Xie X 

PROVIDER: S-EPMC6026779 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature