New Kids on the Block: RNA-Based Influenza Virus Vaccines.

ABSTRACT: RNA-based immunization strategies have emerged as promising alternatives to conventional vaccine approaches. A substantial body of published work demonstrates that RNA vaccines can elicit potent, protective immune responses against various pathogens. Consonant with its huge impact on public health, influenza virus is one of the best studied targets of RNA vaccine research. Currently licensed influenza vaccines show variable levels of protection against seasonal influenza virus strains but are inadequate against drifted and pandemic viruses. In recent years, several types of RNA vaccines demonstrated efficacy against influenza virus infections in preclinical models. Additionally, comparative studies demonstrated the superiority of some RNA vaccines over the currently used inactivated influe

SUBMITTER: Scorza FB 

PROVIDER: S-EPMC6027361 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature