Large Scale Proteomic Data and Network-Based Systems Biology Approaches to Explore the Plant World.

ABSTRACT: The investigation of plant organisms by means of data-derived systems biology approaches based on network modeling is mainly characterized by genomic data, while the potential of proteomics is largely unexplored. This delay is mainly caused by the paucity of plant genomic/proteomic sequences and annotations which are fundamental to perform mass-spectrometry (MS) data interpretation. However, Next Generation Sequencing (NGS) techniques are contributing to filling this gap and an increasing number of studies are focusing on plant proteome profiling and protein-protein interactions (PPIs) identification. Interesting results were obtained by evaluating the topology of PPI networks in the context of organ-associated biological processes as well as plant-pathogen relationships. These examples fo

SUBMITTER: Di Silvestre D 

PROVIDER: S-EPMC6027444 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature