Estimating the prevalence of schistosomiasis japonica in China: a serological approach.

ABSTRACT:

Background

The prevalence of schistosomiasis japonica has decreased significantly, and the responses changing from control to elimination in Jiangsu Province, P.R. China. How to estimate the change in prevalence of schistosomiasis using only serological data will be important and useful.

Methods

We collected serum samples from 2011 to 2015 to build a serum bank from Dantu County of Jiangsu, China. Serum samples were detected by enzyme-linked immunosorbent assay (ELISA), the positive rate and optical density (OD) value were obtained. The Bayesian model including the prior information of sensitivity and specificity of ELISA was established, and the estimated infection rates were obtained for different years, genders and age groups.

Results

There was no significant diffe

SUBMITTER: Wang XY 

PROVIDER: S-EPMC6027568 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature