Dependency and health utilities in stroke: Data to inform cost-effectiveness analyses.

ABSTRACT:

Introduction

Health utilities (HU) assign preference weights to specific health states and are required for cost-effectiveness analyses. Existing HU for stroke inadequately reflect the spectrum of post-stroke disability. Using international stroke trial data, we calculated HU stratified by disability to improve precision in future cost-effectiveness analyses.

Materials and methods

We used European Quality of Life Score (EQ-5D-3L) data from the Virtual International Stroke Trials Archive (VISTA) to calculate HU, stratified by modified Rankin Scale scores (mRS) at 3 months. We applied published value sets to generate HU, and validated these using ordinary least squares regression, adjusting for age and baseline National Institutes of Health Stroke Scale (NIHSS) scores.

Resu

SUBMITTER: Ali M 

PROVIDER: S-EPMC6027777 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature