Cytomegalovirus infection and outcome in immunocompetent patients in the intensive care unit: a systematic review and meta-analysis.

ABSTRACT:

Background

Cytomegalovirus (CMV) infection is common in immunocompetent patients in intensive care units (ICUs). However, whether CMV infection or CMV reactivation contributes to mortality of immunocompetent patients remains unclear.

Methods

A literature search was conducted for relevant studies published before May 30, 2016. Studies reporting on CMV infection in immunocompetent patients in ICUs and containing 2 × 2 tables on CMV results and all-cause mortality were included.

Results

Eighteen studies involving 2398 immunocompetent patients admitted to ICUs were included in the meta-analysis. The overall rate of CMV infection was 27% (95%CI 22-34%, I² = 89%, n = 2398) and the CMV reactivation was 31% (95%CI 24-39%, I² = 74%, n = 666). The odds rat

SUBMITTER: Li X 

PROVIDER: S-EPMC6027797 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature