Genomic Model with Correlation Between Additive and Dominance Effects.

ABSTRACT: Dominance genetic effects are rarely included in pedigree-based genetic evaluation. With the availability of single nucleotide polymorphism markers and the development of genomic evaluation, estimates of dominance genetic effects have become feasible using genomic best linear unbiased prediction (GBLUP). Usually, studies involving additive and dominance genetic effects ignore possible relationships between them. It has been often suggested that the magnitude of functional additive and dominance effects at the quantitative trait loci are related, but there is no existing GBLUP-like approach accounting for such correlation. Wellmann and Bennewitz (2012) showed two ways of considering directional relationships between additive and dominance effects, which they estimated in a Bayesian framewor

SUBMITTER: Xiang T 

PROVIDER: S-EPMC6028252 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature