Coronary atherosclerosis in indigenous South American Tsimane: a cross-sectional cohort study.

ABSTRACT:

Background

Conventional coronary artery disease risk factors might potentially explain at least 90% of the attributable risk of coronary artery disease. To better understand the association between the pre-industrial lifestyle and low prevalence of coronary artery disease risk factors, we examined the Tsimane, a Bolivian population living a subsistence lifestyle of hunting, gathering, fishing, and farming with few cardiovascular risk factors, but high infectious inflammatory burden.

Methods

We did a cross-sectional cohort study including all individuals who self-identified as Tsimane and who were aged 40 years or older. Coronary atherosclerosis was assessed by coronary artery calcium (CAC) scoring done with non-contrast CT in Tsimane adults. We assessed the difference betwee

SUBMITTER: Kaplan H 

PROVIDER: S-EPMC6028773 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature