Evaluation of a commercial multi-dimensional echocardiography technique for ventricular volumetry in small animals.

ABSTRACT:

Background

The assessment of ventricular volumes using conventional echocardiography methods is limited with regards to the need of geometrical assumptions. In the present study, we aimed to evaluate a novel commercial system for three-dimensional echocardiography (3DE) in preclinical models by direct comparison with conventional 1D- and 2D-echocardiography (1DE; 2DE) and the gold-standard technique magnetic resonance imaging (MRI). Further, we provide a standard operating protocol for image acquisition and analysis with 3DE.

Methods

3DE was carried out using a 30 MHz center frequency transducer coupled to a Vevo®3100 Imaging System. We evaluated under different experimental conditions: 1) in vitro phantom measurements served as controlled setting in which boundaries were cl

SUBMITTER: Grune J 

PROVIDER: S-EPMC6029342 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature