Discriminant Value of Custom Ocular Response Analyzer Waveform Derivatives in Forme Fruste Keratoconus.

ABSTRACT:

Purpose

To evaluate the performance of corneal hysteresis (CH), corneal resistance factor (CRF), 37 Ocular Response Analyzer (ORA) waveform parameters, and 15 investigator-derived ORA variables in differentiating forme fruste keratoconus (KC) from normal corneas.

Design

Case-control study.

Methods

Seventy-eight eyes of 78 unaffected patients and 21 topographically normal eyes of 21 forme fruste KC patients with topographically manifest KC in the contralateral eye were matched for age, the thinnest point of the cornea, central corneal thickness, and maximum keratometry. Fifteen candidate variables were derived from exported ORA signals to characterize putative indicators of biomechanical behavior, and 37 waveform parameters were tested. Differences between groups were

SUBMITTER: Luz A 

PROVIDER: S-EPMC6029869 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature