Ontology highlight
ABSTRACT:
SUBMITTER: Rosati E
PROVIDER: S-EPMC6030253 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Frontiers in oncology 20180627
Chronic lymphocytic leukemia (CLL) is an incurable B-cell neoplasm characterized by highly variable clinical outcomes. In recent years, genomic and molecular studies revealed a remarkable heterogeneity in CLL, which mirrored the clinical diversity of this disease. These studies profoundly enhanced our understanding of leukemia cell biology and led to the identification of new biomarkers with potential prognostic and therapeutic significance. Accumulating evidence indicates a key role of deregula ...[more]