MOLEonline: a web-based tool for analyzing channels, tunnels and pores (2018 update).

ABSTRACT: MOLEonline is an interactive, web-based application for the detection and characterization of channels (pores and tunnels) within biomacromolecular structures. The updated version of MOLEonline overcomes limitations of the previous version by incorporating the recently developed LiteMol Viewer visualization engine and providing a simple, fully interactive user experience. The application enables two modes of calculation: one is dedicated to the analysis of channels while the other was specifically designed for transmembrane pores. As the application can use both PDB and mmCIF formats, it can be leveraged to analyze a wide spectrum of biomacromolecular structures, e.g. stemming from NMR, X-ray and cryo-EM techniques. The tool is interconnected with other bioinformatics tools (e.g., PDBe, CS

SUBMITTER: Pravda L 

PROVIDER: S-EPMC6030847 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature