SWISS-MODEL: homology modelling of protein structures and complexes.

ABSTRACT: Homology modelling has matured into an important technique in structural biology, significantly contributing to narrowing the gap between known protein sequences and experimentally determined structures. Fully automated workflows and servers simplify and streamline the homology modelling process, also allowing users without a specific computational expertise to generate reliable protein models and have easy access to modelling results, their visualization and interpretation. Here, we present an update to the SWISS-MODEL server, which pioneered the field of automated modelling 25 years ago and been continuously further developed. Recently, its functionality has been extended to the modelling of homo- and heteromeric complexes. Starting from the amino acid sequences of the interacting protei

SUBMITTER: Waterhouse A 

PROVIDER: S-EPMC6030848 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature