CoNekT: an open-source framework for comparative genomic and transcriptomic network analyses.

ABSTRACT: The recent accumulation of gene expression data in the form of RNA sequencing creates unprecedented opportunities to study gene regulation and function. Furthermore, comparative analysis of the expression data from multiple species can elucidate which functional gene modules are conserved across species, allowing the study of the evolution of these modules. However, performing such comparative analyses on raw data is not feasible for many biologists. Here, we present CoNekT (Co-expression Network Toolkit), an open source web server, that contains user-friendly tools and interactive visualizations for comparative analyses of gene expression data and co-expression networks. These tools allow analysis and cross-species comparison of (i) gene expression profiles; (ii) co-expression networks; (

SUBMITTER: Proost S 

PROVIDER: S-EPMC6030989 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature