Serum-to-dialysate potassium gradient and its association with short-term outcomes in hemodialysis patients.

ABSTRACT:

Background

A high serum-to-dialysate potassium (K+) gradient at the start of dialysis leads to rapid lowering of serum K+ and may confer a greater risk of adverse events. Here, we examined the near-term association of K+ gradient with clinical outcomes.

Methods

This retrospective (2010-11) event-based study considered 830 741 patient-intervals, each defined by a pre-dialysis measurement of serum K+ made among adult Medicare Parts A and B enrollees who received in-center hemodialysis on a Monday/Wednesday/Friday schedule at a large US dialysis organization. K+ gradient was considered based on the difference in K+ concentration (serum-dialysate) on the date of measurement; analyses accounted for multiple observations per patient. Outcomes considered were: all-cause and cardiov

SUBMITTER: Brunelli SM 

PROVIDER: S-EPMC6031041 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature