Antibody and cytokine response to Cystoisospora suis infections in immune-competent young pigs.

ABSTRACT:

Background

To date, investigations on the immune response to Cystoisospora suis infections focused on suckling piglets, the age group clinically most affected. Actively immunizing piglets is unfeasible due to their immature immune system and the typically early infection in the first days after birth. Therefore, understanding and possibly enhancing the immune response of immune-competent animals is the prerequisite to develop a passive immunization strategy for piglets which currently rely on very limited treatment options.

Methods

To investigate antibody and cytokine responses of immune-competent animals and the impact of the oral immunization protocol on their immune response, growers with unknown previous exposure to C. suis (10-11 weeks-old) were infected one or three ti

SUBMITTER: Freudenschuss B 

PROVIDER: S-EPMC6031197 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature