Self-Reported Tobacco, Alcohol, and Illicit Drug Use and Progression of Chronic Kidney Disease.

ABSTRACT:

Background and objectives

Previous studies suggest that tobacco, alcohol, and illicit drug use is associated with CKD. We examined the associations of substance use with CKD progression and all-cause mortality among patients with CKD.

Design, setting, participants, & measurements

The Chronic Renal Insufficiency Cohort Study is a prospective, longitudinal cohort study among 3939 participants with CKD in the United States. Self-reported tobacco smoking, alcohol drinking, marijuana use, and hard illicit drug (cocaine, heroin, or methamphetamine) use were obtained at baseline and annual follow-up visits. CKD progression was defined as incident ESKD or halving of eGFR. Substance use was modeled as the cumulative average exposure to capture both recent and long-term use in multiva

SUBMITTER: Bundy JD 

PROVIDER: S-EPMC6032576 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature