Increased Burden of Psychiatric Disorders in Rheumatoid Arthritis.

ABSTRACT: OBJECTIVE:We estimated the incidence and prevalence of depression, anxiety disorder, bipolar disorder, and schizophrenia in a population-based cohort with rheumatoid arthritis (RA) as compared to an age-, sex-, and geographically matched cohort without RA. METHODS:Using population-based administrative health data from Manitoba, Canada, we identified persons with incident RA between 1989 and 2012, and a cohort from the general population matched 5:1 on year of birth, sex, and region of residence. We applied validated algorithms for depression, anxiety disorder, bipolar disorder, and schizophrenia to determine the annual incidence of these conditions after the diagnosis of RA, and their lifetime and annual period prevalence. We compared findings between cohorts using negative binomial regres

SUBMITTER: Marrie RA 

PROVIDER: S-EPMC6033023 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature