Green Tea Liquid Consumption Alters the Human Intestinal and Oral Microbiome.

ABSTRACT:

Scope

GTPs (green tea polyphenols) exert anti-CRC (colorectal cancer) activity. The intestinal microbiota and intestinal colonization by bacteria of oral origin has been implicated in colorectal carcinogenesis. GT modulates the composition of mouse gut microbiota harmonious with anticancer activity. Therefore, the effect of green tea liquid (GTL) consumption on the gut and oral microbiome is investigated in healthy volunteers (n = 12).

Methods and results

16S sequencing and phylogenetic investigation of communities by reconstruction of unobserved states (PICRUSt) analysis of both fecal and saliva samples (collected before intervention, after 2 weeks of GTL (400 mL per day) and after a washout period of one week) in healthy volunteers show changes in microbial diversity and c

SUBMITTER: Yuan X 

PROVIDER: S-EPMC6033105 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature