Serum copper levels are associated with bone mineral density and total fracture.

ABSTRACT:

Background

Both copper deficiency and overexposure have been associated with adverse health effects. Evidence linking copper to bone mineral density (BMD) and total fracture, however, is limited.

Methods

This nationally representative cross-sectional study enrolled participants from the National Health and Nutrition Examination Survey (2011-2014) in the United States. Using unadjusted and multivariate adjusted logistic regression analyses and a two-piecewise linear regression model with a smoothing function, we evaluated the associations between serum copper levels, bone mineral density and total fracture in 722 participants.

Results

The study sample (n = 722, mean age: 56.47 ± 11.55 y) represented a population of which 47.2% were men; 43.91% were non-Hispanic white,

SUBMITTER: Qu X 

PROVIDER: S-EPMC6034109 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature