Assessment of outcome measures for cost-utility analysis in depression: mapping depression scales onto the EQ-5D-5L.

ABSTRACT:

Background

Many clinical studies including mental health interventions do not use a health state utility instrument, which is essential for producing quality-adjusted life years. In the absence of such utility instrument, mapping algorithms can be applied to estimate utilities from a disease-specific instrument.AimsWe aim to develop mapping algorithms from two widely used depression scales; the Depression Anxiety Stress Scales (DASS-21) and the Kessler Psychological Distress Scale (K-10), onto the most widely used health state utility instrument, the EQ-5D-5L, using eight country-specific value sets.

Method

A total of 917 respondents with self-reported depression were recruited to describe their health on the DASS-21 and the K-10 as well as the new five-level version of the

SUBMITTER: Gamst-Klaussen T 

PROVIDER: S-EPMC6034447 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature