Ablation dynamics during laser interstitial thermal therapy for mesiotemporal epilepsy.

ABSTRACT:

Introduction

The recent emergence of laser interstitial thermal therapy (LITT) as a frontline surgical tool in the management of brain tumors and epilepsy is a result of advances in MRI thermal imaging. A limitation to further improving LITT is the diversity of brain tissue thermoablative properties, which hinders our ability to predict LITT treatment-related effects. Utilizing the mesiotemporal lobe as a consistent anatomic model system, the goal of this study was to use intraoperative thermal damage estimate (TDE) maps to study short- and long-term effects of LITT and to identify preoperative variables that could be helpful in predicting tissue responses to thermal energy.

Methods

For 30 patients with mesiotemporal epilepsy treated with LITT at a single institution, intrao

SUBMITTER: Jermakowicz WJ 

PROVIDER: S-EPMC6034782 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature