Pregnant women co-infected with HIV and Zika: Outcomes and birth defects in infants according to maternal symptomatology.

ABSTRACT:

Background

Zika virus (ZIKV) was first isolated in Uganda in 1947. In Brazil, the first reported case of ZIKV infection was in May 2015. Additionally, dengue (DENV) is endemic and there has been a recent outbreak of chikungunya (CHIKV). Since the clinical manifestations of different arboviral infections (AI) can be similar, definitive diagnosis requires laboratory testing.

Objectives

To determine the prevalence of ZIKV, DENV, and CHIKV infections in a Brazilian cohort of HIV-infected pregnant women, to assess clinical/immunological characteristics and pregnancy outcomes of women with evidence of recent AI.

Study design

Laboratory diagnosis of ZIKV, DENV and CHIKV infections utilized serological assays, RT-PCR and PRNT. The tests were performed at the first visit, 34-3

SUBMITTER: Joao EC 

PROVIDER: S-EPMC6034846 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature