Response of cord blood cells to environmental, hereditary and perinatal factors: A prospective birth cohort study.

ABSTRACT:

Background

Many studies investigating the impact of individual risk factors on cord blood immune cell counts may be biased given that cord blood composition is influenced by a multitude of factors. The aim of this study was to comprehensively investigate the relative impact of environmental, hereditary and perinatal factors on cord blood cells.

Methods

In 295 neonates from the prospective Basel-Bern Infant Lung Development Cohort, we performed complete blood counts and fluorescence-activated cell sorting scans of umbilical cord blood. The associations between risk factors and cord blood cells were assessed using multivariable linear regressions.

Results

The multivariable regression analysis showed that an increase per 10μg/m3 of the average nitrogen dioxide 14 days be

SUBMITTER: Lura MP 

PROVIDER: S-EPMC6034853 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature