Variation in treatment and survival of older patients with non-metastatic breast cancer in five European countries: a population-based cohort study from the EURECCA Breast Cancer Group.

ABSTRACT:

Background

Older patients are poorly represented in breast cancer research and guidelines do not provide evidence based recommendations for this specific group. We compared treatment strategies and survival outcomes between European countries and assessed whether variance in treatment patterns may be associated with variation in survival.

Methods

Population-based study including patients aged ≥ 70 with non-metastatic BC from cancer registries from the Netherlands, Belgium, Ireland, England and Greater Poland. Proportions of local and systemic treatments, five-year relative survival and relative excess risks (RER) between countries were calculated.

Results

In total, 236,015 patients were included. The proportion of stage I BC receiving endocrine therapy ranged from 19.

SUBMITTER: Derks MGM 

PROVIDER: S-EPMC6035184 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature