Novel Functional MRI Task for Studying the Neural Correlates of Upper Limb Tremor.

ABSTRACT: Introduction: Tremor of the upper limbs is a disabling symptom that is present during several neurological disorders and is currently without treatment. Functional MRI (fMRI) is an essential tool to investigate the pathophysiology of tremor and aid the development of treatment options. However, no adequately or standardized protocols for fMRI exists at present. Here we present a novel, online available fMRI task that could be used to assess the in vivo pathology of tremor. Objective: This study aims to validate the tremor-evoking potential of the fMRI task in a small group of tremor patients outside the scanner and assess the reproducibility of the fMRI task related activation in healthy controls. Methods: Twelve HCs were scanned at two time points (baseline and

SUBMITTER: Boonstra FMC 

PROVIDER: S-EPMC6036145 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature