Elevated Aggression and Reduced White Matter Integrity in Mild Traumatic Brain Injury: A DTI Study.

ABSTRACT: Mild traumatic brain injury (mTBI) remains the most commonly reported head injury in the United States, and is associated with a wide range of post-concussive symptoms including physical, cognitive and affective impairments. Elevated aggression has been documented in mTBI; however, the neural mechanisms associated with aggression at the chronic stage of recovery remain poorly understood. In the present study, we investigated the association between white matter integrity and aggression in mTBI using diffusion tensor imaging (DTI). Twenty-six age-matched adults participated in the study, including 16 healthy controls (HCs) and 10 individuals in the chronic stage of recovery (either 6-months or 12 months post-mTBI). Psychological measures of aggression included the Buss-Perry Aggression Ques

SUBMITTER: Dailey NS 

PROVIDER: S-EPMC6036267 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature