Influence of respiratory motion management technique on radiation pneumonitis risk with robotic stereotactic body radiation therapy.

ABSTRACT:

Purpose/objectives

For lung stereotactic body radiation therapy (SBRT), real-time tumor tracking (RTT) allows for less radiation to normal lung compared to the internal target volume (ITV) method of respiratory motion management. To quantify the advantage of RTT, we examined the difference in radiation pneumonitis risk between these two techniques using a normal tissue complication probability (NTCP) model.

Materials/method

20 lung SBRT treatment plans using RTT were replanned with the ITV method using respiratory motion information from a 4D-CT image acquired at the original simulation. Risk of symptomatic radiation pneumonitis was calculated for both plans using a previously derived NTCP model. Features available before treatment planning that identified significant increa

SUBMITTER: Chapman CH 

PROVIDER: S-EPMC6036380 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature