Impact of lymph node ratio in selecting patients with resected gastric cancer for adjuvant therapy.

ABSTRACT:

Background

The impact of adjuvant chemotherapy and chemo-radiation therapy in the treatment of resectable gastric cancer remains varied. We sought to define the clinical impact of lymph node ratio on the relative benefit of adjuvant chemotherapy or chemo-radiation therapy among patients having undergone curative-intent resection for gastric cancer.

Methods

Using the multi-institutional US Gastric Cancer Collaborative database, 719 patients with gastric adenocarcinoma who underwent curative-intent resection between 2000 and 2013 were identified. Patients with metastasis or an R2 margin were excluded. The impact of lymph node ratio on overall survival among patients who received chemotherapy or chemo-radiation therapy was evaluated.

Results

Median patient age was 65 yea

SUBMITTER: Kim Y 

PROVIDER: S-EPMC6036903 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature