Visible light-mediated difluoroalkylation of electron-deficient alkenes.

ABSTRACT: A method for the reductive difluoroalkylation of electron-deficient alkenes using 1,1-difluorinated iodides mediated by irradiation with blue light is described. The reaction involves radical addition of 1,1-difluorinated radicals at the double bond followed by hydrogen atom transfer from sodium cyanoborohydride.

SUBMITTER: Supranovich VI 

PROVIDER: S-EPMC6036985 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature