Multimodality quantitative assessments of myocardial perfusion using dynamic contrast enhanced magnetic resonance and ¹⁵O-labelled water positron emission tomography imaging.

ABSTRACT: Kinetic modelling of myocardial perfusion imaging data allows the absolute quantification of myocardial blood flow (MBF) and can improve the diagnosis and clinical assessment of coronary artery disease (CAD). Positron emission tomography (PET) imaging is considered the reference standard technique for absolute quantification, whilst oxygen-15 (¹⁵O)-water has been extensively implemented for MBF quantification. Dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) has also been used for MBF quantification and showed comparable diagnostic performance against (¹⁵O)-water PET studies. We investigated for the first time the diagnostic performance of two different PET MBF analysis softwares PMOD and Carimas, for obstructive CAD detection against invasive clinical s

SUBMITTER: Papanastasiou G 

PROVIDER: S-EPMC6037289 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature