The prevalence of endoscopic gastric mucosal damage in patients with rheumatoid arthritis.

ABSTRACT:

Objectives

Rheumatoid arthritis (RA) patients often take non-steroidal anti-inflammatory drugs (NSAIDs) and corticosteroids as supportive drugs. In this study, we investigated the prevalence of endoscopic gastric damage and their prescribed medications under an actual clinical condition.

Methods

We collected the data of 1704 RA patients who underwent upper gastrointestinal fiberscopy. Gastric mucosal erosion and ulcer were classified using modified LANZA score. We analyzed these data with a multiple regression analysis.

Results

The prevalence of endoscopic gastric mucosal damage in these RA patients was 16.7% (285 cases). A multiple regression analysis indicated that prednisolone (PSL), NSAIDs and proton pump inhibitors (PPIs) were independent risk factors associated

SUBMITTER: Tsujimoto S 

PROVIDER: S-EPMC6037345 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature