Racemic mefloquinium chloro-difluoro-acetate: crystal structure and Hirshfeld surface analysis.

ABSTRACT: In the racemic title mol-ecular salt, C₁₇H₁₇F₆N₂O⁺·C₂ClF₂O₃^- (systematic name: 2-{[2,8-bis-(tri-fluoro-meth-yl)quinolin-4-yl](hy-droxy)meth-yl}piperidin-1-ium chloro-difluoro-acetate), the cation, which is protonated at the piperidine N atom, has the shape of the letter, L, with the piperidin-1-ium group being approximately orthogonal to the quinolinyl residue [the C_q-C_m-C_m-N_a (q = quinolinyl; m = methine; a = ammonium) torsion angle is 177.79 (18)°]. An intra-molecular, charge-assisted ammonium-N-H⋯O(hydrox-yl) hydrogen bond ensures the hy-droxy-O and ammonium-N atoms lie to the same side of the mol-ecule [O_h-

SUBMITTER: Wardell JL 

PROVIDER: S-EPMC6038619 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature