Use of Urea Wash ELISA to Distinguish Zika and Dengue Virus Infections.
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ABSTRACT:
SUBMITTER: Tsai WY
PROVIDER: S-EPMC6038735 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
Publications
Use of Urea Wash ELISA to Distinguish Zika and Dengue Virus Infections.
Tsai Wen-Yang WY Youn Han Ha HH Tyson Jasmine J Brites Carlos C Tsai Jih-Jin JJ Pedroso Celia C Drexler Jan Felix JF Balmaseda Angel A Harris Eva E Wang Wei-Kung WK
Emerging infectious diseases 20180701 7
Serologic testing remains crucial for Zika virus diagnosis. We found that urea wash in a Zika virus nonstructural protein 1 IgG ELISA distinguishes secondary dengue virus infection from Zika virus infection with previous dengue (sensitivity 87.5%, specificity 93.8%). This test will aid serodiagnosis, serosurveillance, and monitoring of Zika complications in dengue-endemic regions. ...[more]
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2017-09-18 | GSE103932 | GEO