Use of Urea Wash ELISA to Distinguish Zika and Dengue Virus Infections.

ABSTRACT: Serologic testing remains crucial for Zika virus diagnosis. We found that urea wash in a Zika virus nonstructural protein 1 IgG ELISA distinguishes secondary dengue virus infection from Zika virus infection with previous dengue (sensitivity 87.5%, specificity 93.8%). This test will aid serodiagnosis, serosurveillance, and monitoring of Zika complications in dengue-endemic regions.

SUBMITTER: Tsai WY 

PROVIDER: S-EPMC6038735 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature